GORASP2 抗体 (AA 151-250) (Biotin)
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- 抗原 See all GORASP2 抗体
- GORASP2 (Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2))
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抗原表位
- AA 151-250
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适用
- 小鼠, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GORASP2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 非洲爪蟾
- 预测反应
- Human,Rat,Cow,Sheep,Pig,Horse,Rabbit,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Golgi phosphoprotein 6
- 亚型
- IgG
- Top Product
- Discover our top product GORASP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GORASP2 (Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2))
- 别名
- Golgi phosphoprotein 6 (GORASP2 产品)
- 别名
- MGC53281 antibody, MGC132131 antibody, MGC73072 antibody, zgc:73072 antibody, DKFZp459O1715 antibody, 0610011A07Rik antibody, 2410043M02Rik antibody, 5730520M13Rik antibody, 9430094F20Rik antibody, AW552058 antibody, GOLPH2 antibody, GRASP55 antibody, GRS2 antibody, p59 antibody, Grs2 antibody, GOLPH6 antibody, golgi reassembly stacking protein 2 L homeolog antibody, golgi reassembly stacking protein 2 antibody, gorasp2.L antibody, gorasp2 antibody, GORASP2 antibody, CC1G_02936 antibody, Gorasp2 antibody
- 背景
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Synonyms: Golgi phosphoprotein 6, Golgi reassembly stacking protein 2, Golgi reassembly stacking protein 2, 55 kDa, Golgi reassembly stacking protein of 55 kDa, Golgi reassembly-stacking protein 2, Golgi reassembly-stacking protein of 55 kDa, GOLPH2, GOLPH6, GORASP2, GORS2_HUMAN, GRASP55, GRS2, p59, RP23-428O15.1.
Background: The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
- 基因ID
- 26003
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