GUCY1A1 抗体 (AA 301-400) (Biotin)
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- 抗原 See all GUCY1A1 抗体
- GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
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抗原表位
- AA 301-400
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GUCY1A1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1
- 亚型
- IgG
- Top Product
- Discover our top product GUCY1A1 Primary Antibody
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anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 22-214) antibody
GUCY1A1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3G6B2 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 20-152) antibodyGUCY1A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 269-300), (N-Term) antibodyGUCY1A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB07757 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) antibodyGUCY1A1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-690) antibodyGUCY1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 41-140) antibodyGUCY1A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-120) antibodyGUCY1A1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 301-400) antibodyGUCY1A1 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (Internal Region) antibodyGUCY1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1) (AA 1-690) antibodyGUCY1A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))
- Abstract
- GUCY1A1 产品
- 别名
- GC-SA3 antibody, GUC1A3 antibody, GUCA3 antibody, GUCSA3 antibody, GUCY1A1 antibody, 1200016O07Rik antibody, Gucy1a1 antibody, SGC antibody, im:7136149 antibody, sgc1a1 antibody, zgc:112159 antibody, gucy1a3 antibody, guanylate cyclase 1 soluble subunit alpha antibody, guanylate cyclase 1, soluble, alpha 3 antibody, guanylate cyclase 1 soluble subunit alpha 3 antibody, soluble guanylyl cyclase alpha subunit antibody, GUCY1A3 antibody, Gucy1a3 antibody, gucy1a3 antibody
- 背景
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Synonyms: GUCA3, MYMY6, GC-SA3, GUC1A3, GUCSA3, GUCY1A1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3
Background: Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
- 基因ID
- 2982
- UniProt
- Q02108
- 途径
- Myometrial Relaxation and Contraction
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