WDFY1 抗体 (AA 21-120) (Biotin)
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- 抗原 See all WDFY1 抗体
- WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))
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抗原表位
- AA 21-120
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WDFY1 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human WDFY1
- 亚型
- IgG
- Top Product
- Discover our top product WDFY1 Primary Antibody
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anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (AA 261-357) antibody
WDFY1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (AA 42-91) antibodyWDFY1 适用: 人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠, Bat, 小鸡 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (N-Term) antibodyWDFY1 适用: 人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠, 斑马鱼, 小鸡 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-WD Repeat and FYVE Domain Containing 1 (WDFY1) (N-Term) antibodyWDFY1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))
- 别名
- WDFY1 + WDFY2 (WDFY1 产品)
- 别名
- FENS-1 antibody, WDF1 antibody, ZFYVE17 antibody, 1700013B03Rik antibody, 1700120F24Rik antibody, Jr1 antibody, mKIAA1435 antibody, MGC93914 antibody, zgc:101764 antibody, zgc:109909 antibody, WD repeat and FYVE domain containing 1 antibody, WDFY1 antibody, Wdfy1 antibody, wdfy1 antibody
- 背景
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Synonyms: FENS 1, FENS-1, FENS1, KIAA1435, Phosphoinositide binding protein 1, Phosphoinositide binding protein SR1, Phosphoinositide-binding protein 1, WD repeat and FYVE domain containing 1, WD repeat and FYVE domain-containing protein 1, WD40 and FYVE domain containing protein 1, WD40- and FYVE domain-containing protein 1, WDF1, WDFY1, WDFY1_HUMAN, ZFYVE17, Zinc finger FYVE domain containing protein 17, Zinc finger FYVE domain-containing protein 17, WDFY2, WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein, WD40- and FYVE domain-containing protein 2, Zinc finger FYVE domain-containing protein 22, WDF2, ZFYVE22
Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDFY1 positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. WDFY1 Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines. WDFY2 acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2. WDFY2 positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1
- 基因ID
- 57590, 115825
- UniProt
- Q8IWB7, Q96P53
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