ALKBH1 抗体 (AA 1-100) (Biotin)
-
- 抗原 See all ALKBH1 抗体
- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
-
抗原表位
- AA 1-100
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ALKBH1 antibody is conjugated to Biotin
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ABH1/ALKB
- 亚型
- IgG
- Top Product
- Discover our top product ALKBH1 Primary Antibody
-
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibody
ALKBH1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibodyALKBH1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 97-146) antibodyALKBH1 适用: 人, 小鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (Center) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (N-Term) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
- 别名
- ABH1/ALKB (ALKBH1 产品)
- 别名
- Alkbh antibody, ABH antibody, ABH1 antibody, ALKBH antibody, alkB antibody, hABH antibody, 2700073G19Rik antibody, Abh antibody, alkB homolog 1, histone H2A dioxygenase antibody, Alkbh1 antibody, ALKBH1 antibody
- 背景
-
Synonyms: ABH, ABH1, alkB, AlkB, alkylation repair homolog 1 E. coli, ALKB1_HUMAN, ALKBH, ALKBH1, Alkylated DNA repair protein alkB homolog 1, Alkylation repair homolog 1, Alkylation repair, alkB homolog, Alpha-ketoglutarate-dependent dioxygenase ABH1, DNA lyase ABH1, hABH.
Background: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
- 基因ID
- 8846
- 途径
- DNA Damage Repair
-
