SIX2 抗体 (AA 101-200) (Biotin)
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- 抗原 See all SIX2 抗体
- SIX2 (SIX Homeobox 2 (SIX2))
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIX2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SIX2
- 亚型
- IgG
- Top Product
- Discover our top product SIX2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SIX2 (SIX Homeobox 2 (SIX2))
- 别名
- SIX2 (SIX2 产品)
- 别名
- six2-A antibody, zgc:195089 antibody, zgc:195096 antibody, six2.1 antibody, wu:fj04e08 antibody, zgc:91945 antibody, SIX homeobox 2 antibody, sine oculis-related homeobox 2 antibody, SIX homeobox 2 S homeolog antibody, SIX homeobox 2b antibody, SIX homeobox 2a antibody, SIX2 antibody, Six2 antibody, six2.S antibody, six2b antibody, six2a antibody
- 背景
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Synonyms: Homeobox protein SIX2, OTTHUMP00000201649, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, SIX homeobox 2, Six2, SIX2_HUMAN.
Background: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.
- 基因ID
- 10736
- 途径
- Protein targeting to Nucleus
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