RASA1 抗体 (AA 451-550) (Biotin)
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- 抗原 See all RASA1 抗体
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
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抗原表位
- AA 451-550
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASA1 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1
- 亚型
- IgG
- Top Product
- Discover our top product RASA1 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
- 别名
- RASA1 (RASA1 产品)
- 别名
- CG9209 antibody, D-RasGAP antibody, Dmel\\CG9209 antibody, RAS-GAP antibody, RasGAP antibody, RasGap antibody, rasGap antibody, CM-AVM antibody, CMAVM antibody, GAP antibody, PKWS antibody, RASA antibody, RASGAP antibody, p120GAP antibody, p120RASGAP antibody, GAPX antibody, Rasa antibody, Gap antibody, vacuolar peduncle antibody, RAS p21 protein activator 1 antibody, vap antibody, RASA1 antibody, Rasa1 antibody
- 背景
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Synonyms: Ras GAP, CM AVM, CMAVM, DKFZp434N071, GAP, GTPase activating protein, GTPase-activating protein, OTTHUMP00000222390, OTTHUMP00000222391, OTTHUMP00000222392, OTTHUMP00000222393, p120GAP, p120RASGAP, PKWS, Ras GTPase-activating protein 1, RAS p21 protein activator GTPase activating protein 1, Ras p21 protein activator, RASA, RASA1, RASA1_HUMAN, RasGAP, Triphosphatase activating protein.
Background: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
- 基因ID
- 5921
- 途径
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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