GEMIN7 抗体 (AA 21-120) (Biotin)
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- 抗原 See all GEMIN7 抗体
- GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
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抗原表位
- AA 21-120
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GEMIN7 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Gemin 7
- 亚型
- IgG
- Top Product
- Discover our top product GEMIN7 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))
- 别名
- Gemin 7 (GEMIN7 产品)
- 别名
- SIP3 antibody, GEMIN7 antibody, Gemin7 antibody, 2400008I04Rik antibody, AI120175 antibody, AI461688 antibody, gem nuclear organelle associated protein 7 antibody, gem (nuclear organelle) associated protein 7 antibody, GEMIN7 antibody, Gemin7 antibody
- 背景
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Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.
Background: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
- 基因ID
- 79760
- 途径
- Ribonucleoprotein Complex Subunit Organization
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