ARID1B 抗体 (AA 1501-1600) (Biotin)
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- 抗原 See all ARID1B 抗体
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
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抗原表位
- AA 1501-1600
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARID1B antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ARID1B
- 亚型
- IgG
- Top Product
- Discover our top product ARID1B Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
- 别名
- ARID1B (ARID1B 产品)
- 别名
- fd07d11 antibody, si:dkey-60a16.3 antibody, wu:fd07d11 antibody, 8030481M12 antibody, 9330189K18Rik antibody, AI836955 antibody, Ardi1b antibody, B230217J03Rik antibody, mKIAA1235 antibody, 6A3-5 antibody, Smcf1 antibody, smcf-1 antibody, BAF250B antibody, BRIGHT antibody, DAN15 antibody, ELD/OSA1 antibody, MRD12 antibody, OSA2 antibody, P250R antibody, AT rich interactive domain 1B (SWI1-like) antibody, AT rich interactive domain 1B (SWI-like) antibody, AT-rich interaction domain 1B antibody, arid1b antibody, Arid1b antibody, ARID1B antibody
- 背景
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Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235
Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
- 基因ID
- 57492
- UniProt
- Q8NFD5
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