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GAS41 抗体 (AA 151-227) (Biotin)

适用: 小鼠, 非洲爪蟾 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1700497
发货至: 中国
  • 抗原 See all GAS41 products
    GAS41 (YEATS Domain Containing 4)
    抗原表位
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-227
    适用
    • 51
    • 41
    • 15
    • 14
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    小鼠, 非洲爪蟾
    宿主
    • 55
    • 10
    克隆类型
    • 57
    • 8
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAS41 antibody is conjugated to Biotin
    应用范围
    • 49
    • 23
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 非洲爪蟾
    预测反应
    Human,Rat,Cow,Horse,Chicken,Rabbit,Zebrafish
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GAS41
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    GAS41 (YEATS Domain Containing 4)
    别名
    GAS41 (GAS41 产品)
    背景

    Synonyms: 4930573H17Rik, B230215M10Rik, GAS 41, Gas41, glioma amplied sequence 41, Glioma-amplied sequence 41, glioma-amplied sequence-41, gliomaamplied sequence 41, gliomaamplied sequence41, NUBI 1, NuBI-1, NuBI1, NuMA binding protein 1, NuMA-binding protein 1, YAF9, YEATS domain containing 4, YEATS domain containing4, YEATS domain-containing protein 4, YEATS4, YETS4_HUMAN.

    Background: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias, and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (Integrase Interactor), which is a human homologue of the yeast SNF5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.

    基因ID
    8089
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