ORC1 抗体 (Biotin)
-
- 抗原 See all ORC1 (ORC1L) 抗体
- ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))
- 适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ORC1 antibody is conjugated to Biotin
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ORC1L/ORC1
- 亚型
- IgG
- Top Product
- Discover our top product ORC1L Primary Antibody
-
anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibody
ORC1L 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibodyORC1L 适用: 人 WB, IP 宿主: 大鼠 Monoclonal 7A7 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 1-110) antibodyORC1L 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (Internal Region) antibodyORC1L 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 1-110) antibodyORC1L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) antibodyORC1L 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal 7F6-1 unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 170-220) antibodyORC1L 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Origin Recognition Complex, Subunit 1 (ORC1L) (AA 696-856) antibodyORC1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))
- 别名
- ORC1L (ORC1L 产品)
- 别名
- CG10667 antibody, DmORC1 antibody, DmOrc1 antibody, DmOrc1p antibody, Dmel\\CG10667 antibody, ORC antibody, ORC1 antibody, dORC1 antibody, orc1 antibody, rDmORC antibody, ORC1L antibody, HSORC1 antibody, PARC1 antibody, orc1l antibody, xorc1 antibody, AA545195 antibody, MmORC1 antibody, Orc1l antibody, Origin recognition complex subunit 1 antibody, origin recognition complex subunit 1 antibody, origin recognition complex subunit 1 L homeolog antibody, origin recognition complex, subunit 1 antibody, Orc1 antibody, ORC1 antibody, orc1.L antibody
- 背景
-
Synonyms: HSORC1, MmORC1, orc1, ORC1_HUMAN, ORC1L, Origin Recognition Complex 1, Origin recognition complex subunit 1 yeast homolog like, Origin recognition complex subunit 1, Origin recognition complex subunit 1 homolog, Origin recognition complex subunit 1 like S. cerevisia, Origin recognition complex subunit 1 like, Origin recognition complex subunit 1 S. cerevisiae homolog like, Origin recognition complex, subunit 1 like yeast, PARC1, Replication control protein 1.
Background: The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle, however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
- 基因ID
- 4998
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
-
