GEMIN6 抗体 (AA 21-120) (Biotin)
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- 抗原 See all GEMIN6 抗体
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
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抗原表位
- AA 21-120
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GEMIN6 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Gemin 6
- 亚型
- IgG
- Top Product
- Discover our top product GEMIN6 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
- 别名
- Gemin 6 (GEMIN6 产品)
- 别名
- 2610019B15Rik antibody, 2810470M17Rik antibody, gemin6 antibody, gem nuclear organelle associated protein 6 antibody, gem (nuclear organelle) associated protein 6 antibody, gem nuclear organelle associated protein 6 S homeolog antibody, GEMIN6 antibody, Gemin6 antibody, gemin6.S antibody
- 背景
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Synonyms: FLJ23459, Gemin6, Gemin-6, Gem nuclear organelle associated protein 6, Gem-associated protein 6, GEMI6, GEMI6_HUMAN, Gemin-6, GEMIN6, SIP2.
Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
- 基因ID
- 79833
- 途径
- Ribonucleoprotein Complex Subunit Organization
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