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GART 抗体 (AA 281-380) (Biotin)

This anti-GART antibody is a 兔 多克隆 antibody detecting GART in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1700302
发货至: 中国

Quick Overview for GART 抗体 (AA 281-380) (Biotin) (ABIN1700302)

抗原

GART (Phosphoribosylglycinamide Formyltransferase (GART))

适用

  • 48
  • 25
  • 13
  • 2

宿主

  • 45
  • 4

克隆类型

  • 37
  • 12
多克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GART antibody is conjugated to Biotin

应用范围

  • 20
  • 14
  • 13
  • 7
  • 6
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-380

    预测反应

    Human,Mouse,Rat,Dog,Cow,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GART

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    GART (Phosphoribosylglycinamide Formyltransferase (GART))

    别名

    GART

    背景

    Synonyms: 5'-phosphoribosylglycinamide transformylase, AIR synthase, AIRS, GAR transformylase, GARS, GART, GART, GARTF, Glycinamide ribonucleotide synthetase, MGC47764, PAIS, PGFT, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide synthetase, PRGS, PUR2_HUMAN, Trifunctional purine biosynthetic protein adenosine 3.

    Background: Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events.

    基因ID

    2618

    UniProt

    P22102
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