GADL1 抗体 (AA 51-150) (Biotin)
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- 抗原 See all GADL1 products
- GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))
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抗原表位
- AA 51-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GADL1 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Bee
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GADL1
- 亚型
- IgG
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anti-Glutamate Decarboxylase-Like 1 (GADL1) (AA 215-264) antibody
GADL1 适用: 人, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Decarboxylase-Like 1 (GADL1) (Middle Region) antibodyGADL1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))
- 别名
- GADL1 (GADL1 产品)
- 别名
- CSAD antibody, 1110027M19Rik antibody, RGD1565145 antibody, glutamate decarboxylase like 1 antibody, glutamate decarboxylase-like 1 antibody, GADL1 antibody, gadl1 antibody, Gadl1 antibody
- 背景
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Synonyms: GADL1, GADL1_HUMAN, Glutamate decarboxylase like 1, Glutamate decarboxylase-like protein 1, MGC138191, OTTHUMP00000161199, OTTHUMP00000222306.
Background: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
- 基因ID
- 339896
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