CUTC 抗体 (AA 201-273) (Biotin)
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- 抗原 See all CUTC 抗体
- CUTC (CutC Copper Transporter Homolog (CUTC))
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抗原表位
- AA 201-273
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CUTC antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CUTC
- 亚型
- IgG
- Top Product
- Discover our top product CUTC Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CUTC (CutC Copper Transporter Homolog (CUTC))
- 别名
- CUTC (CUTC 产品)
- 别名
- zgc:103406 antibody, RP11-483F11.3 antibody, 2310039I18Rik antibody, AI326282 antibody, CGI-32 antibody, cutC copper transporter antibody, cutC copper transporter homolog (E. coli) antibody, CUTC antibody, cutc antibody, Cutc antibody
- 背景
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Synonyms: CGI 32, CGI32, Copper homeostasis protein cutC homolog, cutC, CutC copper transporter homolog E. coli, CUTC_HUMAN, RP11-483F11.3.
Background: Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
- 基因ID
- 51076
- 途径
- Transition Metal Ion Homeostasis
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