CEP57 抗体 (AA 51-150) (Biotin)
-
- 抗原 See all CEP57 抗体
- CEP57 (Centrosomal Protein 57kDa (CEP57))
-
抗原表位
- AA 51-150
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CEP57 antibody is conjugated to Biotin
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CEP57
- 亚型
- IgG
- Top Product
- Discover our top product CEP57 Primary Antibody
-
-
- 应用备注
-
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- CEP57 (Centrosomal Protein 57kDa (CEP57))
- 别名
- CEP57 (CEP57 产品)
- 别名
- 3110002L15RIK antibody, CEP57 antibody, cep57r antibody, xCep57 antibody, c6orf182 antibody, 3110002l15rik antibody, RGD1309884 antibody, 3110002L15Rik antibody, 4921510P06Rik antibody, 4931428M20Rik antibody, AI467480 antibody, Tsp57 antibody, mKIAA0092 antibody, MVA2 antibody, PIG8 antibody, TSP57 antibody, centrosomal protein 57 antibody, centrosomal protein 57kDa-like 1 antibody, CEP57 antibody, cep57l1 antibody, Cep57 antibody
- 背景
-
Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.
Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.
- 途径
- M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
-