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DOK7 抗体 (AA 21-120) (Biotin)

DOK7 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1700158
发货至: 中国
  • 抗原 See all DOK7 抗体
    DOK7 (Docking Protein 7 (DOK7))
    抗原表位
    • 14
    • 9
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 31
    • 26
    • 15
    大鼠
    宿主
    • 47
    • 4
    • 1
    • 1
    克隆类型
    • 49
    • 4
    多克隆
    标记
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOK7 antibody is conjugated to Biotin
    应用范围
    • 42
    • 22
    • 13
    • 13
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DOK7
    亚型
    IgG
    Top Product
    Discover our top product DOK7 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    DOK7 (Docking Protein 7 (DOK7))
    别名
    DOK7 (DOK7 产品)
    别名
    si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody
    背景

    Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.

    Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.

    途径
    Skeletal Muscle Fiber Development
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