STAP2 抗体 (AA 151-250) (Biotin)
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- 抗原 See all STAP2 抗体
- STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))
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抗原表位
- AA 151-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAP2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human STAP2
- 亚型
- IgG
- Top Product
- Discover our top product STAP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- STAP2 (Signal Transducing Adaptor Family Member 2 (STAP2))
- 别名
- STAP2 (STAP2 产品)
- 别名
- BKS antibody, AW049765 antibody, STAP-2 antibody, wu:fa55b07 antibody, zgc:77021 antibody, cb901 antibody, stap2 antibody, wu:fd15d07 antibody, zgc:63913 antibody, signal transducing adaptor family member 2 antibody, signal transducing adaptor family member 2b antibody, signal transducing adaptor family member 2a antibody, STAP2 antibody, Stap2 antibody, stap2b antibody, stap2a antibody
- 背景
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Synonyms: BKS, Breast tumor kinase substrate, BRK substrate, Signal transducing adaptor protein 2, Signal-transducing adaptor protein 2, Ssignal transducing adaptor family member 2, STAP 2, STAP-2, STAP2, STAP2_HUMAN.
Background: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
- 基因ID
- 55620
- UniProt
- Q9UGK3
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