BPY2 抗体 (AA 51-106) (Biotin)
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- 抗原 See all BPY2 抗体
- BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
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抗原表位
- AA 51-106
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BPY2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BPY2
- 亚型
- IgG
- Top Product
- Discover our top product BPY2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- BPY2 (Basic Charge, Y-Linked, 2 (BPY2))
- 别名
- BPY2 (BPY2 产品)
- 别名
- BPY2A antibody, VCY2 antibody, VCY2A antibody, basic charge, Y-linked, 2 antibody, BPY2 antibody
- 背景
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Synonyms: Basic charge, Basic charge Y linked 2, Basic charge Y linked 2C, Basic protein on Y chromosome 2, BPY2A, BPY2B, BPY2C, Testis specic basic protein on Y 2, Testis specic basic protein Y 2, Testis-specic basic protein Y 2, Variable charge Y linked 2, Variably charged protein Y 2, VCY2, VCY2_HUMAN, VCY2A, VCY2B, VCY2C, Y-linked 2.
Background: Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.
- 基因ID
- 442867
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