Protein C Light Chain (AA 131-230) 抗体 (AbBy Fluor® 647)
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- 抗原
- Protein C Light Chain
- 抗原表位
- AA 131-230
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- AbBy Fluor® 647
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Vitamin K-dependent protein C light chain
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Protein C Light Chain
- 背景
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Synonyms: Protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, PROC, PROC1, Vitamin K dependent protein C precursor, APC, EC 3.4.21.69, PC, proC, PROC_HUMAN, Protein C inactivator of coagulation factors Va and VIIIa, Vitamin K dependent protein C, Vitamin K-dependent protein C, Vitamin K-dependent protein C light chain.
Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].
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