EXTL3 抗体 (AA 351-450) (AbBy Fluor® 647)
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- 抗原 See all EXTL3 抗体
- EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
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抗原表位
- AA 351-450
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXTL3 antibody is conjugated to AbBy Fluor® 647
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EXTL3
- 亚型
- IgG
- Top Product
- Discover our top product EXTL3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))
- 别名
- EXTL3 (EXTL3 产品)
- 别名
- BcDNA:LD21192 antibody, Botv antibody, CG15110 antibody, DEXT3 antibody, DEXTL3 antibody, Dextl3 antibody, Dmel\\CG15110 antibody, Extl3 antibody, 2900009G18Rik antibody, AU040105 antibody, Ext1l antibody, mKIAA0519 antibody, BOTV antibody, EXTL1L antibody, EXTR1 antibody, REGR antibody, RPR antibody, Regr antibody, brother of tout-velu antibody, exostoses (multiple)-like 3 antibody, exostosin like glycosyltransferase 3 antibody, exostosin-like glycosyltransferase 3 antibody, botv antibody, Extl3 antibody, EXTL3 antibody
- 背景
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Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.
Background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.
- 基因ID
- 2137
- 途径
- Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling
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