CRTAP 抗体 (AA 201-300) (AbBy Fluor® 647)
-
- 抗原 See all CRTAP 抗体
- CRTAP (Cartilage Associated Protein (CRTAP))
-
抗原表位
- AA 201-300
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CRTAP antibody is conjugated to AbBy Fluor® 647
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CRTAP
- 亚型
- IgG
- Top Product
- Discover our top product CRTAP Primary Antibody
-
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- CRTAP (Cartilage Associated Protein (CRTAP))
- 别名
- CRTAP (CRTAP 产品)
- 别名
- zgc:85621 antibody, wu:fb47h01 antibody, CASP antibody, LEPREL3 antibody, OI7 antibody, 5730529N23Rik antibody, Leprel3 antibody, RGD1565180 antibody, cartilage associated protein antibody, cartilage-associated protein antibody, crtap antibody, CRTAP antibody, LOC5574430 antibody, CpipJ_CPIJ013810 antibody, Crtap antibody
- 背景
-
Synonyms: Cartilage associated protein, LEPREL3, leprecan-like 3, CASP, CRTAP_HUMAN.
Background: CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.
- 基因ID
- 10491
-