AFAP1L2 抗体 (AbBy Fluor® 647)
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- 抗原 See all AFAP1L2 抗体
- AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AFAP1L2 antibody is conjugated to AbBy Fluor® 647
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AFAP1L2
- 亚型
- IgG
- Top Product
- Discover our top product AFAP1L2 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
- 别名
- Afap1l2 (AFAP1L2 产品)
- 别名
- KIAA1914 antibody, XB130 antibody, AU041783 antibody, C86904 antibody, mKIAA1914 antibody, RGD1310668 antibody, actin filament associated protein 1 like 2 antibody, actin filament associated protein 1-like 2 antibody, AFAP1L2 antibody, Afap1l2 antibody
- 背景
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Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.
Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
- 途径
- EGFR Signaling Pathway
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