EYA3 抗体 (AA 371-470) (AbBy Fluor® 555)
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- 抗原 See all EYA3 抗体
- EYA3 (Eyes Absent Homolog 3 (EYA3))
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抗原表位
- AA 371-470
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EYA3 antibody is conjugated to AbBy Fluor® 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EYA3
- 亚型
- IgG
- Top Product
- Discover our top product EYA3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- EYA3 (Eyes Absent Homolog 3 (EYA3))
- 别名
- EYA3 (EYA3 产品)
- 别名
- zgc:152966 antibody, si:ch211-195b13.2 antibody, Xeya3 antibody, MGC85199 antibody, EYA3 antibody, AI844637 antibody, EYA transcriptional coactivator and phosphatase 3 antibody, EYA transcriptional coactivator and phosphatase 3 L homeolog antibody, eya3 antibody, eya3.L antibody, EYA3 antibody, Eya3 antibody
- 背景
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Synonyms: AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog Drosophila, Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1.
Background: EYA3 is a 573 amino acid protein that localizes to both the nucleus and the cytoplasm and is one of several mammalian homologs of the Drosophila Eya (eyes absent) protein. Existing as two alternatively spliced isoforms, EYA3 possesses magnesium-catalyzed phosphatase activity and is thought to play a role in transcriptional regulation during organogenesis. Specifically, EYA3 interacts with proteins such as Six1 and, via this interaction, functions to activate the expression of genes that are involved in cellular proliferation and organ development. Upon DNA damage, EYA3 may be phosphorylated by ATM or ATR. The gene encoding EYA3 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8 % of the human genome.
- 基因ID
- 2140
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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