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NOB1 抗体 (AbBy Fluor® 555)

NOB1 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN1696745
发货至: 中国
  • 抗原 See all NOB1 抗体
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    适用
    • 52
    • 23
    • 20
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 51
    • 2
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 21
    • 6
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
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    This NOB1 antibody is conjugated to AbBy Fluor® 555
    应用范围
    • 43
    • 20
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NOB1
    亚型
    IgG
    Top Product
    Discover our top product NOB1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    别名
    NOB1 (NOB1 产品)
    别名
    MEE6.26 antibody, MEE6_26 antibody, Nob1p antibody, fc27e05 antibody, si:ch73-167i17.3 antibody, wu:fc27e05 antibody, ART-4 antibody, MST158 antibody, NOB1P antibody, PSMD8BP1 antibody, 1700021I09Rik antibody, Psmd8bp1 antibody, NIN1/PSMD8 binding protein 1 homolog antibody, RNA-binding NOB1-like protein antibody, RNA-binding protein nob1 antibody, RNA-binding protein NOB1 antibody, NIN1/RPN12 binding protein 1 homolog S homeolog antibody, NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) antibody, NIN1/RPN12 binding protein 1 homolog antibody, NOB1 antibody, AT5G41190 antibody, EDI_130960 antibody, CpipJ_CPIJ012739 antibody, BDBG_01281 antibody, PAAG_04204 antibody, PITG_13300 antibody, nob1.S antibody, nob1 antibody, Nob1 antibody
    背景

    Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.

    Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.

    基因ID
    28987
    途径
    Protein targeting to Nucleus
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