CLEC12A 抗体 (AA 61-160) (AbBy Fluor® 555)
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- 抗原 See all CLEC12A 抗体
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
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抗原表位
- AA 61-160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLEC12A antibody is conjugated to AbBy Fluor® 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CLEC12A
- 亚型
- IgG
- Top Product
- Discover our top product CLEC12A Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- 别名
- CLEC12A (CLEC12A 产品)
- 别名
- MGC179455 antibody, CLL-1 antibody, CLL1 antibody, DCAL-2 antibody, MICL antibody, D230024O04 antibody, KLRL1 antibody, Micl antibody, C-type lectin domain family 12 member A antibody, C-type lectin domain family 12, member a antibody, C-type lectin domain family 12, member A antibody, CLEC12A antibody, Clec12a antibody
- 背景
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Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CL12A_HUMAN, CLEC12A, CLL-1, DCAL-2, Dendritic cell-associated lectin 2, MICL, Myeloid inhibitory C-type lectin-like receptor.
Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer.
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