GALNS 抗体 (AA 1-100) (AbBy Fluor® 488)
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- 抗原 See all GALNS 抗体
- GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GALNS antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GALNS
- 亚型
- IgG
- Top Product
- Discover our top product GALNS Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
- 别名
- GALNS (GALNS 产品)
- 别名
- GALNAC6S antibody, GAS antibody, GalN6S antibody, MPS4A antibody, mFLJ00319 antibody, galns antibody, zgc:158385 antibody, galactosamine (N-acetyl)-6-sulfatase antibody, galactosamine (N-acetyl)-6-sulfate sulfatase antibody, N-acetylgalactosamine-6-sulfatase antibody, galactosamine (N-acetyl)-6-sulfatase L homeolog antibody, GALNS antibody, Galns antibody, Celly_0425 antibody, galns.L antibody, galns antibody
- 背景
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Synonyms: Chondroitinase, Chondroitinsulfatase, FLJ00319, FLJ17434, FLJ42844, FLJ98217, Galactosamine N acetyl 6 sulfate sulfatase, Galactose 6 sulfate sulfatase, GALNAC6S, GalNAc6S sulfatase, GAS, mFLJ00319, MPS4A, N acetylgalactosamine 6 sulfatase, N acetylgalactosamine 6 sulfate sulfatase, GALNS_HUMAN.
Background: Chondroitinase is a 522 amino acid protein that localizes to the lysosome and functions as an exohydrolase that is essential for the degradation of glycosaminoglycans, keratan sulfate and chondroitin 6-sulfate. Using calcium as a cofactor, Chondroitinase, which exists as a disulfide linked oligomer, catalyzes the hydrolysis of the 6-sulfate group on target substrates. Defects in the gene encoding Chondroitinase are the cause of mucopolysaccharidosis type 4A (MPS4A), an autosomal recessive lysosomal storage disease that is characterized by the intracellular accumulation of keratan sulfate and chondroitin-6-sulfate and is associated with dental anomalies, short stature and, in some cases, death in the second or third decade of life.
- 基因ID
- 2588
- 途径
- Glycosaminoglycan Metabolic Process
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