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SIX2 抗体 (AA 101-200) (AbBy Fluor® 488)

SIX2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1695624
发货至: 中国
  • 抗原 See all SIX2 抗体
    SIX2 (SIX Homeobox 2 (SIX2))
    抗原表位
    • 14
    • 9
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 44
    • 13
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 3
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIX2 antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 38
    • 22
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SIX2
    亚型
    IgG
    Top Product
    Discover our top product SIX2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SIX2 (SIX Homeobox 2 (SIX2))
    别名
    SIX2 (SIX2 产品)
    别名
    six2-A antibody, zgc:195089 antibody, zgc:195096 antibody, six2.1 antibody, wu:fj04e08 antibody, zgc:91945 antibody, SIX homeobox 2 antibody, sine oculis-related homeobox 2 antibody, SIX homeobox 2 S homeolog antibody, SIX homeobox 2b antibody, SIX homeobox 2a antibody, SIX2 antibody, Six2 antibody, six2.S antibody, six2b antibody, six2a antibody
    背景

    Synonyms: Homeobox protein SIX2, OTTHUMP00000201649, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, SIX homeobox 2, Six2, SIX2_HUMAN.

    Background: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.

    基因ID
    10736
    途径
    Protein targeting to Nucleus
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