LIMD1 抗体 (AA 21-120) (AbBy Fluor® 488)
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- 抗原 See all LIMD1 抗体
- LIMD1 (LIM Domains Containing 1 (LIMD1))
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抗原表位
- AA 21-120
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIMD1 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Limd1
- 亚型
- IgG
- Top Product
- Discover our top product LIMD1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LIMD1 (LIM Domains Containing 1 (LIMD1))
- 别名
- Limd1 (LIMD1 产品)
- 别名
- AW822033 antibody, D9Ertd192e antibody, xlimd1 antibody, LIM domains containing 1 antibody, LIM domains containing 1 L homeolog antibody, LIMD1 antibody, Limd1 antibody, limd1 antibody, limd1.L antibody
- 背景
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Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.
Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.
- 基因ID
- 8994
- 途径
- Ribonucleoprotein Complex Subunit Organization
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