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C-JUN 抗体 (pThr91, pThr93) (AbBy Fluor® 488)

JUN 适用: 人 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1695296
发货至: 中国
  • 抗原 See all C-JUN (JUN) 抗体
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    抗原表位
    • 45
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    • 37
    • 28
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    • 16
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    • 16
    • 9
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    • 2
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    • 1
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    pThr91, pThr93
    适用
    • 388
    • 203
    • 186
    • 33
    • 27
    • 22
    • 17
    • 16
    • 16
    • 12
    • 11
    • 7
    • 5
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    • 1
    • 1
    宿主
    • 382
    • 14
    • 1
    克隆类型
    • 360
    • 37
    多克隆
    标记
    • 189
    • 22
    • 14
    • 13
    • 13
    • 12
    • 12
    • 12
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    • 12
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    This C-JUN antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 262
    • 131
    • 126
    • 98
    • 63
    • 49
    • 46
    • 43
    • 42
    • 23
    • 11
    • 8
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Thr91/93
    亚型
    IgG
    Top Product
    Discover our top product JUN Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    别名
    c-Jun (JUN 产品)
    别名
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    背景

    Synonyms: p-c-JunThr91+Thr93, p-JunThr91+Thr93, Jun oncogene, JUN, Activator Protein 1, AP 1, AP1, AP-1, Enhancer Binding Protein AP1, Jun Activation Domain Binding Protein, JUN protein, JUNC, p39, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, vJun Avian Sarcoma Virus 17 Oncogene Homolog, JUN_HUMAN, Transcription factor AP-1, Activator 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog.

    Background: C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.

    基因ID
    3725
    途径
    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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