Supervillin 抗体 (AA 51-150) (AbBy Fluor® 488)
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- 抗原 See all Supervillin (SVIL) 抗体
- Supervillin (SVIL)
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抗原表位
- AA 51-150
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Supervillin antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Supervillin
- 亚型
- IgG
- Top Product
- Discover our top product SVIL Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Supervillin (SVIL)
- 别名
- Supervillin (SVIL 产品)
- 别名
- sb:cb867 antibody, svil antibody, wu:fd05a09 antibody, SVIL antibody, DKFZp468F0819 antibody, AU024053 antibody, B430302E16Rik antibody, supervillin a antibody, supervillin antibody, supervillin, putative antibody, svila antibody, SVIL antibody, LOC5577073 antibody, CpipJ_CPIJ003700 antibody, Smp_148580 antibody, svil antibody, Svil antibody
- 背景
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Synonyms: Supervillin, Archvillin, p205/p250, SVIL
Background: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).
- 基因ID
- 6840
- UniProt
- O95425
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