ZBTB46 抗体 (AbBy Fluor® 488)
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- 抗原 See all ZBTB46 (ZNF340) 抗体
- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZBTB46 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Sheep,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4
- 亚型
- IgG
- Top Product
- Discover our top product ZNF340 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
- 别名
- Zbtb46/Btbd4 (ZNF340 产品)
- 背景
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Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.
Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
- 基因ID
- 140685
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