CTBS 抗体 (AA 1-100) (AbBy Fluor® 488)
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- 抗原 See all CTBS 抗体
- CTBS (Chitobiase, Di-N-Acetyl (CTBS))
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抗原表位
- AA 1-100
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTBS antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CTBS
- 亚型
- IgG
- Top Product
- Discover our top product CTBS Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CTBS (Chitobiase, Di-N-Acetyl (CTBS))
- 别名
- CTBS (CTBS 产品)
- 别名
- CTB antibody, 2210401K11Rik antibody, chitobiase antibody, chitobiase, di-N-acetyl- antibody, CTBS antibody, Ctbs antibody
- 背景
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Synonyms: Chitobiase di N acetyl, CTB, Di N acetylchitobiase, OTTHUMP00000011570, DIAC_HUMAN.
Background: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.
- 基因ID
- 1486
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