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Complement C4 抗体 (AA 21-120) (AbBy Fluor® 488)

C4 适用: 人 IF (p), IF (cc) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1694460
发货至: 中国
  • 抗原 See all Complement C4 (C4) 抗体
    Complement C4 (C4) (Complement 4 (C4))
    抗原表位
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 48
    • 6
    • 4
    • 1
    宿主
    • 46
    • 5
    • 4
    • 3
    • 1
    克隆类型
    • 52
    • 7
    多克隆
    标记
    • 27
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Complement C4 antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 25
    • 25
    • 15
    • 13
    • 11
    • 11
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    预测反应
    Human
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Complement C4
    亚型
    IgG
    Top Product
    Discover our top product C4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Complement C4 (C4) (Complement 4 (C4))
    别名
    C4a+C4b (C4 产品)
    别名
    C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, C4-1 antibody, C4b antibody, C4-2 antibody, Slp antibody, Ss antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4A (Rodgers blood group) antibody, complement 4 antibody, complement component 4A antibody, complement component 4B (Chido blood group) antibody, C4B antibody, C4A antibody, C4a antibody, C4 antibody, C4b antibody
    背景

    Synonyms: C4, RG, C4S, CO4, C4A2, C4A3, C4A4, C4A6, C4AD, CPAMD2, CH, C4F, C4B1, C4B2, C4B3, C4B5, C4BD, C4B12, C4B_2, CPAMD3, Complement C4-A, Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A

    Background: Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

    基因ID
    720, 721
    UniProt
    P0C0L4
    途径
    Complement System
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