Cholera Toxin beta 抗体 (AbBy Fluor® 488)
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- 抗原 See all Cholera Toxin beta products
- Cholera Toxin beta
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适用
- Vibrio cholerae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cholera Toxin beta antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 大鼠
- 交叉反应 （详细）
- Cholera Toxin Subunit B
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin
- 亚型
- IgG
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Cholera Toxin beta
- Abstract
- Cholera Toxin beta 产品
- 背景
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Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, TOXB, VC1456, CHTB_VIBCH.
Background: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
- 基因ID
- 2613962
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