电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Clca3 抗体 (AbBy Fluor® 350)

CLCA3 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1694359
发货至: 中国
  • 抗原 See all Clca3 (CLCA3) products
    Clca3 (CLCA3) (Epithelial Chloride Channel Protein (CLCA3))
    适用
    • 14
    • 14
    • 1
    小鼠, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Clca3 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 15
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Mouse,Rat,Dog
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse CLCA3
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Clca3 (CLCA3) (Epithelial Chloride Channel Protein (CLCA3))
    别名
    Clca3 (CLCA3 产品)
    别名
    calcium-activated chloride channel antibody, LOC784768 antibody
    背景

    Synonyms: Calcium activated chloride channel 3, Calcium-activated chloride channel regulator family member 3, Chloride channel accessory 3 pseudogene, chloride channel calcium activated 3, Chloride channel calcium activated family member 3, Clca1, Clca2, CLCA3P, Gob 5, Gob-5, Gob5, hCLCA3, mCLCA3, MGC143984, MGC143985.

    Background: The calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.

You are here:
客服