Glutaredoxin 2 抗体 (AA 101-164) (AbBy Fluor® 350)
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- 抗原 See all Glutaredoxin 2 (GRX2) 抗体
- Glutaredoxin 2 (GRX2)
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抗原表位
- AA 101-164
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutaredoxin 2 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Glutaredoxin 2
- 亚型
- IgG
- Top Product
- Discover our top product GRX2 Primary Antibody
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Glutaredoxin 2 (GRX2)
- 别名
- Glutaredoxin 2 (GRX2 产品)
- 别名
- ECK1049 antibody, JW1051 antibody, CGI-133 antibody, GRX2 antibody, 1700010P22Rik antibody, AI645710 antibody, Grx2 antibody, glutaredoxin 2 (Grx2) antibody, glutaredoxin Grx2 antibody, thioredoxin antibody, glutaredoxin 2 antibody, glutaredoxin 2 (thioltransferase) antibody, grxB antibody, grx2 antibody, AF_RS10790 antibody, GLRX2 antibody, Glrx2 antibody
- 背景
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Synonyms: GRX2, CGI-133, Glutaredoxin-2, mitochondrial, GLRX2
Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
- 基因ID
- 51022
- UniProt
- Q9NS18
- 途径
- Cell RedoxHomeostasis
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