IB2 抗体 (AA 31-130) (AbBy Fluor® 350)
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- 抗原 See all IB2 (JIP-2) 抗体
- IB2 (JIP-2) (C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2))
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抗原表位
- AA 31-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IB2 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Cow,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human JIP2
- 亚型
- IgG
- Top Product
- Discover our top product JIP-2 Primary Antibody
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anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) antibody
JIP-2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) (AA 579-774) antibodyJIP-2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) (C-Term) antibodyJIP-2 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) (AA 581-630) antibodyJIP-2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) (AA 470-570) antibodyJIP-2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2) (AA 307-356) antibodyJIP-2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IB2 (JIP-2) (C-Jun-Amino-Terminal Kinase-Interacting Protein 2 (JIP-2))
- 别名
- JIP2 (JIP-2 产品)
- 别名
- IB2 antibody, JIP2 antibody, PRKM8IPL antibody, 3230402N03Rik antibody, AI847694 antibody, AW049958 antibody, Jip2 antibody, R75148 antibody, mitogen-activated protein kinase 8 interacting protein 2 antibody, MAPK8IP2 antibody, Mapk8ip2 antibody
- 背景
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Synonyms: MAPK8IP2, C jun amino terminal kinase interacting protein 2, C-jun-amino-terminal kinase-interacting protein 2, Homologous to mouse JIP 1, IB 2, IB-2, IB2, Islet brain 2, Islet-brain-2, JIP 2, JIP-2, JIP2, JIP2_HUMAN, JNK interacting protein 2, JNK MAP kinase scaffold protein 2, JNK MAP kinase scaffold protein JIP2, JNK-interacting protein 2, MAPK8IP2, Mitogen activated protein kinase 8 interacting protein 2, Mitogen-activated protein kinase 8-interacting protein 2, PRKM8 interacting protein like, PRKM8IPL.
Background: c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1). JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser-63 and Ser-73, resulting in transcriptional activation (2-5). Two additional JNK family members have been identified as JNK2 and JNK3 (3). JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6). Multiple splice variants if JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain (7).
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