HIC2 抗体 (AA 501-600) (AbBy Fluor® 350)
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- 抗原 See all HIC2 抗体
- HIC2 (Hypermethylated in Cancer 2 (HIC2))
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抗原表位
- AA 501-600
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIC2 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HIC2
- 亚型
- IgG
- Top Product
- Discover our top product HIC2 Primary Antibody
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anti-Hypermethylated in Cancer 2 (HIC2) (Middle Region) antibody
HIC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (AA 1-615) antibodyHIC2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) antibodyHIC2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (AA 1-100) antibodyHIC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (Internal Region) antibodyHIC2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (AA 188-200) antibodyVerified HIC2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (C-Term) antibodyHIC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, 斑马鱼, Bat, 非洲爪蟾, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (N-Term) antibodyHIC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (AA 395-444) antibodyHIC2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hypermethylated in Cancer 2 (HIC2) (AA 252-301) antibodyHIC2 适用: 人, 小鼠, 大鼠, 犬, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- HIC2 (Hypermethylated in Cancer 2 (HIC2))
- 别名
- Hic2 (HIC2 产品)
- 别名
- HIC2 antibody, hic2 antibody, MGC154932 antibody, HRG22 antibody, ZBTB30 antibody, ZNF907 antibody, AA409108 antibody, mKIAA1020 antibody, zgc:109776 antibody, HIC ZBTB transcriptional repressor 2 antibody, hypermethylated in cancer 2 L homeolog antibody, hypermethylated in cancer 2 antibody, HIC2 antibody, hic2.L antibody, Hic2 antibody, hic2 antibody
- 背景
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Synonyms: HIC1 related gene on chromosome 22, HIC2, Hic3, HRG22, Hypermethylated in cancer 2 protein, KIAA1020, ZBTB30, Zinc finger and BTB domain-containing protein 30, ZNF907, HIC2_HUMAN.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.
- 基因ID
- 23119
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