NOSTRIN 抗体 (AA 301-400) (AbBy Fluor® 350)
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- 抗原 See all NOSTRIN 抗体
- NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))
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抗原表位
- AA 301-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOSTRIN antibody is conjugated to AbBy Fluor® 350
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NOSTRIN
- 亚型
- IgG
- Top Product
- Discover our top product NOSTRIN Primary Antibody
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anti-Nitric Oxide Synthase Trafficker (NOSTRIN) (AA 1-245) antibody
NOSTRIN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase Trafficker (NOSTRIN) (AA 18-251) antibodyNOSTRIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase Trafficker (NOSTRIN) (AA 1-322) antibodyNOSTRIN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase Trafficker (NOSTRIN) (AA 6-245) antibodyNOSTRIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase Trafficker (NOSTRIN) (AA 207-506) antibodyNOSTRIN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))
- 别名
- Nostrin (NOSTRIN 产品)
- 别名
- NOSTRIN antibody, MGC171848 antibody, Daip2 antibody, mDaIP2 antibody, DaIP2 antibody, nitric oxide synthase trafficking antibody, nitric oxide synthase trafficking L homeolog antibody, nitric oxide synthase trafficker antibody, NOSTRIN antibody, nostrin antibody, nostrin.L antibody, Nostrin antibody
- 背景
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Synonyms: BM247, BM247 homolog, DaIP2, eNOS-trafficking inducer, mDaIP2, MGC20702, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, NOSTN_HUMAN, Nostrin, RP23-431D4.2
Background: NOSTRIN (nitric oxide synthase trafficker isoform 1), also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins. NOSTRIN is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. It consists of an N-terminal Cdc15 domain with an FCH (Fes/CIP homology) region, two coiled coil domains and a C-terminal SH3 domain. NOSTRIN typically exists as a trimer. It functions as an adaptor protein binding to caveolin-1 via an internal domain and NOS3 via its SH3 domain, forming a ternary complex which facilitates caveolar transport of NOS3. The NOS3 protein is responsible for the production of nitric oxide (NO), a potent mediator in various biological processes. The translocation of NOS3 from the plasma membrane to intracellular vesicle-like structures diminishes NO production. NOSTRIN also interacts with Dynamin and N-WASP via its SH3 domain.
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