电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Chloride Channel 5 抗体 (AA 1-100) (AbBy Fluor® 350)

CLCN5 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1692977
发货至: 中国
  • 抗原 See all Chloride Channel 5 (CLCN5) 抗体
    Chloride Channel 5 (CLCN5)
    抗原表位
    • 14
    • 14
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 48
    • 14
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 48
    • 1
    克隆类型
    • 49
    多克隆
    标记
    • 16
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chloride Channel 5 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 23
    • 22
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
    亚型
    IgG
    Top Product
    Discover our top product CLCN5 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Chloride Channel 5 (CLCN5)
    别名
    Chloride Channel 5 (CLCN5 产品)
    别名
    CLCN3 antibody, CLCN5 antibody, clcn5-A antibody, DKFZp469O2315 antibody, 5430408K11Rik antibody, ClC-5 antibody, Clc5 antibody, D930009B12Rik antibody, DXImx42e antibody, Sfc13 antibody, T25545 antibody, CLC5 antibody, CLCK2 antibody, DENTS antibody, NPHL1 antibody, NPHL2 antibody, XLRH antibody, XRN antibody, hCIC-K2 antibody, CLCN4 antibody, Clcn5 antibody, chloride voltage-gated channel 5 antibody, chloride channel, voltage-sensitive 5 L homeolog antibody, chloride channel, voltage-sensitive 5 antibody, CLCN5 antibody, clcn5.L antibody, clcn5 antibody, Clcn5 antibody
    背景

    Synonyms: Chloride channel protein 5, Chloride transporter ClC-5, ClC-5, CLC5, CLCK2, CLCN5, CLCN5_HUMAN, DENTS, H+/Cl- exchange transporter 5, hCIC-K2, NPHL1, NPHL2, XLRH, XRN.

    Background: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent?s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.

You are here:
客服