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DC-SIGN/CD209 抗体 (APC)

CD209 适用: 人 FACS 宿主: 小鼠 Monoclonal UW60-1 APC
产品编号 ABIN1690742
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This DC-SIGN/CD209 antibody is conjugated to APC
    应用范围
    • 72
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    CD209-His-tagged fusion protein
    克隆位点
    UW60-1
    亚型
    IgG2a
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 溶解方式
    No reconstitution is necessary.
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Ryan, Marshall, Magaletti, Floyd, Draves, Olson, Clark: "Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5638-48, (2002) (PubMed).

  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    CD209 (CD209 产品)
    别名
    CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
    背景
    CD209 Molecule,CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).,CLEC4L, DC-SIGN1, CDSIGN
    基因ID
    30835
    UniProt
    Q9NNX6
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