(4 references)-
- 抗原 See all ENPP3 抗体
- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ENPP3 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- HEK-293 cells transfected with human CD203c
- 克隆位点
- NP4D6
- 亚型
- IgG1
- Top Product
- Discover our top product ENPP3 Primary Antibody
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anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 45-163) antibodyENPP3 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 4C1H2 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibodyENPP3 适用: 人, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibodyENPP3 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal NP4D6 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (PE)ENPP3 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal NP4D6 PE
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (APC)ENPP3 适用: 人 FACS 宿主: 小鼠 Monoclonal NP4D6 APC
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 40-140) antibodyENPP3 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 602-699) antibodyENPP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibodyENPP3 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
- 说明
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." in: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).
: "The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3." in: Blood, Vol. 97, Issue 10, pp. 3303-5, (2001) (PubMed).
: "The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors." in: Blood, Vol. 94, Issue 7, pp. 2343-56, (1999) (PubMed).
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: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).
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- 抗原
- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
- 别名
- CD203c (ENPP3 产品)
- 别名
- B10 antibody, CD203c antibody, NPP3 antibody, PD-IBETA antibody, PDNP3 antibody, Npp3 antibody, RB13-6 antibody, AI876438 antibody, ENPP3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog antibody, ENPP3 antibody, Enpp3 antibody, enpp3 antibody, enpp3.L antibody
- 背景
- Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA
- 基因ID
- 5169
- UniProt
- O14638
- 途径
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
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