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PDE8A 抗体

PDE8A 适用: 人 WB 宿主: 小鼠 Monoclonal EM-52 unconjugated
产品编号 ABIN1690735
发货至: 中国
  • 抗原 See all PDE8A 抗体
    PDE8A (phosphodiesterase 8A (PDE8A))
    适用
    • 41
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 38
    • 3
    小鼠
    克隆类型
    • 39
    • 2
    单克隆
    标记
    • 24
    • 5
    • 5
    • 3
    • 2
    • 2
    This PDE8A antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 23
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    Western Blotting (WB)
    特异性
    The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human PDE8a
    克隆位点
    EM-52
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDE8A Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    PDE8A (phosphodiesterase 8A (PDE8A))
    别名
    PDE8a (PDE8A 产品)
    背景
    Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
    基因ID
    5151
    UniProt
    O60658
    途径
    cAMP Metabolic Process
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