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SETD2 抗体 (AA 803-1103)

Name: SETD2 抗体 (AA 803-1103)
Brand: antibodies-online
SKU: ABIN1682666
Availability: OutOfStock

SETD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cells, using SETD2 antibody. (SETD2 抗体 (AA 803-1103))

Immunofluorescence analysis of C6 cells using SETD2 Polyclonal Antibody (ABIN3017564, ABIN3017565, ABIN1682666 and ABIN6220156) at dilution of 1:100 (40x lens). (SETD2 抗体 (AA 803-1103))

Immunofluorescence analysis of A549 cell using SETD2 antibody. (SETD2 抗体 (AA 803-1103))

Regenerative potential and expression of hnRNPL, Setd2 and H3K36me3 in the healing of bone defects filled with MBG and Sr-MBG. (SETD2 抗体 (AA 803-1103))

IHC

AKT pathway was activated by SrCl2 stimulation in PDLCs. (SETD2 抗体 (AA 803-1103))

HnRNPL has negative effect on PDLCs osteogenic differentiation. (SETD2 抗体 (AA 803-1103))

Setd2 promotes PDLCs osteogenic differentiation stimulated by Sr. (SETD2 抗体 (AA 803-1103))

Western blot analysis of extracts of Mouse spleen, using SETD2 antibody (ABIN3017564, ABIN3017565, ABIN1682666 and ABIN6220156) at 1:913 dilution. (SETD2 抗体 (AA 803-1103))

Immunoprecipitation analysis of 600 μg extracts of Mouse spleen using 3 μg SETD2 antibody (ABIN3017564, ABIN3017565, ABIN1682666 and ABIN6220156). (SETD2 抗体 (AA 803-1103))

Immunofluorescence analysis of U-2 OS cells using SETD2 Polyclonal Antibody (ABIN3017564, ABIN3017565, ABIN1682666 and ABIN6220156) at dilution of 1:100 (40x lens). (SETD2 抗体 (AA 803-1103))

10 images

(4 references)

产品编号 ABIN1682666

发货至: 中国

Datasheet as PDF

抗原 See all SETD2 抗体

SETD2 (SET Domain Containing 2 (SETD2))
抗原表位
10

7

2

1

1

1

1

1
AA 803-1103
适用
28

7

6

3

2

2
人
宿主
24

3

1
兔
Compatible Secondaries
克隆类型
25

3
多克隆
标记
16

2

1

1

1

1

1

1

1

1

1

1
This SETD2 antibody is un-conjugated
应用范围
13

11

11

10

6

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

序列

SLCNSEAENI EPSVMKISSN SFMNVHLESK PVICDSRNLT DHSKFACEEY KQSIGSTSSA SVNHFDDLYQ PIGSSGIASS LQSLPPGIKV DSLTLLKCGE NTSPVLDAVL KSKKSSEFLK HAGKETIVEV GSDLPDSGKG FASRENRRNN GLSGKCLQEA QEEGNSILPE RRGRPEISLD ERGEGGHVHT SDDSEVVFSS CDLNLTMEDS DGVTYALKCD SSGHAPEIVS TVHEDYSGSS ESSNDESDSE DTDSDDSSIP RNRLQSVVVV PKNSTLPMEE TSPCSSRSSQ SYRHYSDHWE D

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 803-1103 of human SETD2 (NP_054878.5).

亚型

IgG
anti-SET Domain Containing 2 (SETD2) (AA 2054-2245) antibody
SETD2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4G11E6 unconjugated

anti-SET Domain Containing 2 (SETD2) (Internal Region) antibody
Verified SETD2 适用: 人 ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) (N-Term) antibody
SETD2 适用: 人, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) (N-Term) antibody
SETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) (AA 21-50), (N-Term) antibody
SETD2 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB2780 unconjugated

anti-SET Domain Containing 2 (SETD2) antibody
SETD2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) (AA 323-372) antibody
SETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) antibody
SETD2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) antibody
SETD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-SET Domain Containing 2 (SETD2) (AA 1787-2144) antibody
SETD2 适用: 人 WB 宿主: 小鼠 Monoclonal 1C4 unconjugated

应用备注

WB,1:500 - 1:2000,IF,1:50 - 1:200

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Huang, Gu, Li: "H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation." in: The Journal of biological chemistry, Vol. 293, Issue 20, pp. 7811-7823, (2019) (PubMed).

Jia, Long, Miron, Yin, Wei, Zhang, Wu: "Setd2 is associated with strontium-induced bone regeneration." in: Acta biomaterialia, Vol. 53, pp. 495-505, (2018) (PubMed).

Chen, Liu, Liu, Xia, Zhang, Han, Jiang, Wang, Cao: "Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity." in: Cell, Vol. 170, Issue 3, pp. 492-506.e14, (2017) (PubMed).

Zhu, Lei, Ju, Wang, Huang, Yang, Shao, Zhu, Wei, Fu, Li, Wu: "SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing." in: Nucleic acids research, Vol. 45, Issue 1, pp. 92-105, (2017) (PubMed).
抗原

SETD2 (SET Domain Containing 2 (SETD2))

别名

SETD2 (SETD2 产品)

别名

Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody

背景

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.,SETD2,HBP231,HIF-1,HIP-1,HSPC069,HYPB,KMT3A,LLS,SET2,p231HBP,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,SETD2

分子量

175 kDa/192 kDa/287 kDa

基因ID

29072

UniProt

Q9BYW2

途径

Tube Formation