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NUP98 抗体 (AA 621-920)

NUP98 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1681142
发货至: 中国
  • 抗原 See all NUP98 抗体
    NUP98 (Nucleoporin 98kDa (NUP98))
    抗原表位
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 621-920
    适用
    • 48
    • 17
    • 14
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 12
    • 1
    克隆类型
    • 34
    • 15
    多克隆
    标记
    • 39
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUP98 antibody is un-conjugated
    应用范围
    • 36
    • 16
    • 13
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    SKPVDENHQQ DGDEDSLVSH FYTNPIAKPI PQTPESAGNK HSNSNSVDDT IVALNMRAAL RNGLEGSSEE TSFHDESLQD DREEIENNSY HMHPAGIILT KVGYYTIPSM DDLAKITNEK GECIVSDFTI GRKGYGSIYF EGDVNLTNLN LDDIVHIRRK EVVVYLDDNQ KPPVGEGLNR KAEVTLDGVW PTDKTSRCLI KSPDRLADIN YEGRLEAVSR KQGAQFKEYR PETGSWVFKV SHFSKYGLQD SDEEEEEHPS KTSTKKLKTA PLPPASQTTP LQMALNGKPA PPPQVEKKGQ
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 621-920 of human NUP98 (NP_624357.1).
    亚型
    IgG
    Top Product
    Discover our top product NUP98 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NUP98 (Nucleoporin 98kDa (NUP98))
    别名
    NUP98 (NUP98 产品)
    背景
    Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.,NUP98,ADIR2,NUP196,NUP96,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,NUP98
    分子量
    96 kDa/97 kDa/186 kDa/187 kDa/195 kDa/197 kDa
    基因ID
    4928
    UniProt
    P52948
    途径
    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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