MXD1 antibody, si:dkey-202n14.4 antibody, xmad1 antibody, BHLHC58 antibody, MAD antibody, MAD1 antibody, AW122478 antibody, Mad antibody, Mad1 antibody, Mad-1 antibody, MAX dimerization protein 1 antibody, MAX dimerization protein 1 L homeolog antibody, max dimerization protein 1 antibody, MXD1 antibody, mxd1 antibody, mxd1.L antibody, Mxd1 antibody
背景
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,MXD1,BHLHC58,MAD,MAD1,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,MXD1