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MBD2 抗体 (AA 202-411)

MBD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1680781
发货至: 中国
  • 抗原 See all MBD2 抗体
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    抗原表位
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 202-411
    适用
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 44
    • 2
    • 1
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD2 antibody is un-conjugated
    应用范围
    • 40
    • 22
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DLSSFDFRTG KMMPSKLQKN KQRLRNDPLN QNKGKPDLNT TLPIRQTASI FKQPVTKVTN HPSNKVKSDP QRMNEQPRQL FWEKRLQGLS ASDVTEQIIK TMELPKGLQG VGPGSNDETL LSAVASALHT SSAPITGQVS AAVEKNPAVW LNTSQPLCKA FIVTDEDIRK QEERVQQVRK KLEEALMADI LSRAADTEEM DIEMDSGDEA
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human MBD2 (NP_003918.1).
    亚型
    IgG
    Top Product
    Discover our top product MBD2 Primary Antibody
  • 应用备注
    WB,1:200 - 1:2000
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    别名
    MBD2 (MBD2 产品)
    别名
    MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
    背景
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.,MBD2,DMTase,NY-CO-41,Epigenetics & Nuclear Signaling,MBD2
    分子量
    31 kDa/43 kDa
    基因ID
    8932
    UniProt
    Q9UBB5
    途径
    Chromatin Binding
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