CG11759 antibody, DmKAP antibody, DmKap antibody, Dmel\\CG11759 antibody, KAP antibody, KAP3 antibody, Kap antibody, dKAP3 antibody, kap3 antibody, FLA3 antibody, KAP-1 antibody, KAP-3 antibody, SMAP antibody, Smg-GDS antibody, dJ190I16.1 antibody, fb99h08 antibody, kifap3 antibody, wu:fb99h08 antibody, wz7228 antibody, Kinesin associated protein 3 antibody, kinesin-associated protein 3 antibody, kinesin associated protein 3 antibody, kinesin-associated protein 3b antibody, kinesin-associated protein 3 L homeolog antibody, Kap3 antibody, LOC551999 antibody, KIFAP3 antibody, Kifap3 antibody, kifap3b antibody, kifap3.L antibody
背景
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.,KIFAP3,FLA3,KAP-1,KAP-3,KAP3,SMAP,Smg-GDS,dJ190I16.1,Epigenetics & Nuclear Signaling,KIFAP3