The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.,ITPKB,IP3-3KB,IP3K,IP3K-B,IP3KB,PIG37,Signal Transduction,Neuroscience,Calcium Signaling,ITPKB