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Integrin beta 4 抗体 (AA 28-310)

ITGB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1680489
发货至: 中国
  • 抗原 See all Integrin beta 4 (ITGB4) 抗体
    Integrin beta 4 (ITGB4)
    抗原表位
    • 15
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-310
    适用
    • 81
    • 25
    • 25
    • 3
    • 3
    宿主
    • 55
    • 35
    • 10
    • 2
    克隆类型
    • 52
    • 50
    多克隆
    标记
    • 53
    • 9
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 4 antibody is un-conjugated
    应用范围
    • 50
    • 44
    • 31
    • 31
    • 19
    • 15
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    NRCKKAPVKS CTECVRVDKD CAYCTDEMFR DRRCNTQAEL LAAGCQRESI VVMESSFQIT EETQIDTTLR RSQMSPQGLR VRLRPGEERH FELEVFEPLE SPVDLYILMD FSNSMSDDLD NLKKMGQNLA RVLSQLTSDY TIGFGKFVDK VSVPQTDMRP EKLKEPWPNS DPPFSFKNVI SLTEDVDEFR NKLQGERISG NLDAPEGGFD AILQTAVCTR DIGWRPDSTH LLVFSTESAF HYEADGANVL AGIMSRNDER CHLDTTGTYT QYRTQDYPSV PTL
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 28-310 of human Integrin beta 4 (ITGB4/CD104) (NP_000204.3).
    亚型
    IgG
    Top Product
    Discover our top product ITGB4 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Feng, Chen, Ding, Fu, Yang, Deng, Zeng: "P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite." in: Journal of neuroinflammation, Vol. 12, pp. 190, (2016) (PubMed).

  • 抗原
    Integrin beta 4 (ITGB4)
    别名
    ITGB4 (ITGB4 产品)
    别名
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    背景
    Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,ITGB4,CD104,GP150,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,ITGB4
    分子量
    106 kDa/194 kDa/195 kDa/200 kDa/202 kDa
    基因ID
    3691
    UniProt
    P16144
    途径
    Integrin Complex
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